Identifying collagen VI as a target of fibrotic diseases regulated by CREBBP/EP300

Fibrotic diseases remain a major cause of morbidity and mortality, yet there are few effective therapies. The underlying pathology of all fibrotic conditions is the activity of myofibroblasts. Using cells from freshly excised disease tissue from patients with Dupuytren’s disease (DD), a localized fi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Williams, Lynn M., McCann, Fiona E., Cabrita, Marisa A., Layton, Thomas, Cribbs, Adam, Knezevic, Bogdan, Fang, Hai, Knight, Julian, Zhang, Mingjun, Fischer, Roman, Bonham, Sarah, Steenbeek, Leenart M., Yang, Nan, Sood, Manu, Bainbridge, Chris, Warwick, David, Harry, Lorraine, Davidson, Dominique, Xie, Weilin, Sundstrӧm, Michael, Feldmann, Marc, Nanchahal, Jagdeep
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456151/
https://ncbi.nlm.nih.gov/pubmed/32759223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2004281117
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