Chronic G(q) signaling in AgRP neurons does not cause obesity

Maintaining energy homeostasis requires coordinating physiology and behavior both on an acute timescale to adapt to rapid fluctuations in caloric intake and on a chronic timescale to regulate body composition. Hypothalamic agouti-related peptide (AgRP)-expressing neurons are acutely activated by cal...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Ewbank, Sedona N., Campos, Carlos A., Chen, Jane Y., Bowen, Anna J., Padilla, Stephanie L., Dempsey, Joseph L., Cui, Julia Yue, Palmiter, Richard D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456117/
https://ncbi.nlm.nih.gov/pubmed/32764144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2004941117
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