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Starvation after AgRP neuron ablation is independent of melanocortin signaling

Ablation of inhibitory agouti-related protein (AgRP)-expressing neurons in the arcuate nucleus that also synthesize γ-amino-butyric acid (GABA) and neuropeptide Y in adult mice leads to starvation within 1 week. The removal of inhibition from the AgRP neurons onto neighboring proopiomelanocortin neu...

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Detalhes bibliográficos
Main Authors: Wu, Qi, Howell, Maureen P., Cowley, Michael A., Palmiter, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268197/
https://ncbi.nlm.nih.gov/pubmed/18272480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712062105
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