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In-cell destabilization of a homodimeric protein complex detected by DEER spectroscopy

The complexity of the cellular medium can affect proteins’ properties, and, therefore, in-cell characterization of proteins is essential. We explored the stability and conformation of the first baculoviral IAP repeat (BIR) domain of X chromosome-linked inhibitor of apoptosis (XIAP), BIR1, as a model...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Yang, Yin, Chen, Shen-Na, Yang, Feng, Li, Xia-Yan, Feintuch, Akiva, Su, Xun-Cheng, Goldfarb, Daniella
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456071/
https://ncbi.nlm.nih.gov/pubmed/32788347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2005779117
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