Development of syngeneic murine cell lines for use in immunocompetent orthotopic lung cancer models

BACKGROUND: Immunocompetent animal models are required to study tumor-host interactions, immunotherapy, and immunotherapeutic combinations, however the currently available immunocompetent lung cancer models have substantial limitations. While orthotopic models potentially help fill this gap, the uti...

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Bibliografiske detaljer
Udgivet i:Cancer Cell Int
Main Authors: Nolan, Kyle, Verzosa, Gregory, Cleaver, Tim, Tippimanchai, Darinee, DePledge, Lisa N., Wang, Xiao-Jing, Young, Christian, Le, Anh, Doebele, Robert, Li, Howard, Malkoski, Stephen P.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Primary Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455907/
https://ncbi.nlm.nih.gov/pubmed/32874131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01503-5
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