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Cholesterol 25-hydroxylase protects against experimental colitis in mice by modulating epithelial gut barrier function
Cholesterol 25-hydroxylase (CH25H) encodes the enzyme that converts cholesterol to 25-hydroxycholesterol (25-HC). 25-HC has been demonstrated to be involved in the pathogenesis of inflammatory bowel disease. However, the role of CH25H in experimental colitis remains unknown. Dextran sulfate sodium (...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7455728/ https://ncbi.nlm.nih.gov/pubmed/32859970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71198-1 |
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