Donor myeloid derived suppressor cells (MDSCs) prolong allogeneic cardiac graft survival through programming of recipient myeloid cells in vivo

Solid organ transplantation is a lifesaving therapy for patients with end-organ disease. Current immunosuppression protocols are not designed to target antigen-specific alloimmunity and are uncapable of preventing chronic allograft injury. As myeloid-derived suppressor cells (MDSCs) are potent immun...

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Vydáno v:Sci Rep
Hlavní autoři: Cai, Songjie, Choi, John Y., Borges, Thiago J., Zhang, Hengcheng, Miao, Ji, Ichimura, Takaharu, Li, Xiaofei, Xu, Simiao, Chu, Philip, Eskandari, Siawosh K., Allos, Hazim, Alhaddad, Juliano B., Muhsin, Saif A., Yatim, Karim, Riella, Leonardo V., Sage, Peter T., Chandraker, Anil K., Azzi, Jamil R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455707/
https://ncbi.nlm.nih.gov/pubmed/32859934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71289-z
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