Discovery and Validation of a Urinary Exosome mRNA Signature for the Diagnosis of Human Kidney Transplant Rejection

BACKGROUND: Developing a noninvasive clinical test to accurately diagnose kidney allograft rejection is critical to improve allograft outcomes. Urinary exosomes, tiny vesicles released into the urine that carry parent cells’ proteins and nucleic acids, reflect the biologic function of the parent cel...

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Udgivet i:J Am Soc Nephrol
Main Authors: El Fekih, Rania, Hurley, James, Tadigotla, Vasisht, Alghamdi, Areej, Srivastava, Anand, Coticchia, Christine, Choi, John, Allos, Hazim, Yatim, Karim, Alhaddad, Juliano, Eskandari, Siawosh, Chu, Philip, Mihali, Albana B., Lape, Isadora T., Lima Filho, Mauricio P., Aoyama, Bruno T., Chandraker, Anil, Safa, Kassem, Markmann, James F., Riella, Leonardo V., Formica, Richard N., Skog, Johan, Azzi, Jamil R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2021
Fag:
Clinical Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017553/
https://ncbi.nlm.nih.gov/pubmed/33658284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2020060850
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