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MicroRNA-421 Inhibits Apoptosis by Downregulating Caspase-3 in Human Colorectal Cancer

PURPOSE: Dysregulated microRNAs (miRNAs/miRs) have been reported to play significant roles in pathogenesis of colorectal cancer (CRC). Previous studies have demonstrated that miR-421 regulates apoptosis in some cancers. Caspase-3 plays a key role in apoptosis, but the relationship between miR-421 an...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Zhou, Yifan, Cheng, Xiaowen, Wan, Yufeng, Chen, Tingting, Zhou, Qing, Wang, Zhengguang, Zhu, Huaqing
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455595/
https://ncbi.nlm.nih.gov/pubmed/32904410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S255787
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