Primate-restricted KRAB zinc finger proteins and target retrotransposons control gene expression in human neurons

In the first days of embryogenesis, transposable element–embedded regulatory sequences (TEeRS) are silenced by Kruppel-associated box (KRAB) zinc finger proteins (KZFPs). Many TEeRS are subsequently co-opted in transcription networks, but how KZFPs influence this process is largely unknown. We ident...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Turelli, Priscilla, Playfoot, Christopher, Grun, Dephine, Raclot, Charlène, Pontis, Julien, Coudray, Alexandre, Thorball, Christian, Duc, Julien, Pankevich, Eugenia V., Deplancke, Bart, Busskamp, Volker, Trono, Didier
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455193/
https://ncbi.nlm.nih.gov/pubmed/32923624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba3200
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