The NEMP family supports metazoan fertility and nuclear envelope stiffness

Human genome-wide association studies have linked single-nucleotide polymorphisms (SNPs) in NEMP1 (nuclear envelope membrane protein 1) with early menopause; however, it is unclear whether NEMP1 has any role in fertility. We show that whole-animal loss of NEMP1 homologs in Drosophila, Caenorhabditis...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Tsatskis, Yonit, Rosenfeld, Robyn, Pearson, Joel D., Boswell, Curtis, Qu, Yi, Kim, Kyunga, Fabian, Lacramioara, Mohammad, Ariz, Wang, Xian, Robson, Michael I., Krchma, Karen, Wu, Jun, Gonçalves, João, Hodzic, Didier, Wu, Shu, Potter, Daniel, Pelletier, Laurence, Dunham, Wade H., Gingras, Anne-Claude, Sun, Yu, Meng, Jin, Godt, Dorothea, Schedl, Tim, Ciruna, Brian, Choi, Kyunghee, Perry, John R. B., Bremner, Rod, Schirmer, Eric C., Brill, Julie A., Jurisicova, Andrea, McNeill, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455189/
https://ncbi.nlm.nih.gov/pubmed/32923640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb4591
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