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The NEMP family supports metazoan fertility and nuclear envelope stiffness

Human genome-wide association studies have linked single-nucleotide polymorphisms (SNPs) in NEMP1 (nuclear envelope membrane protein 1) with early menopause; however, it is unclear whether NEMP1 has any role in fertility. We show that whole-animal loss of NEMP1 homologs in Drosophila, Caenorhabditis...

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Publicado en:Sci Adv
Main Authors: Tsatskis, Yonit, Rosenfeld, Robyn, Pearson, Joel D., Boswell, Curtis, Qu, Yi, Kim, Kyunga, Fabian, Lacramioara, Mohammad, Ariz, Wang, Xian, Robson, Michael I., Krchma, Karen, Wu, Jun, Gonçalves, João, Hodzic, Didier, Wu, Shu, Potter, Daniel, Pelletier, Laurence, Dunham, Wade H., Gingras, Anne-Claude, Sun, Yu, Meng, Jin, Godt, Dorothea, Schedl, Tim, Ciruna, Brian, Choi, Kyunghee, Perry, John R. B., Bremner, Rod, Schirmer, Eric C., Brill, Julie A., Jurisicova, Andrea, McNeill, Helen
Formato: Artigo
Idioma:Inglês
Publicado: American Association for the Advancement of Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455189/
https://ncbi.nlm.nih.gov/pubmed/32923640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb4591
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