The NEMP family supports metazoan fertility and nuclear envelope stiffness

Human genome-wide association studies have linked single-nucleotide polymorphisms (SNPs) in NEMP1 (nuclear envelope membrane protein 1) with early menopause; however, it is unclear whether NEMP1 has any role in fertility. We show that whole-animal loss of NEMP1 homologs in Drosophila, Caenorhabditis...

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Gepubliceerd in:Sci Adv
Hoofdauteurs: Tsatskis, Yonit, Rosenfeld, Robyn, Pearson, Joel D., Boswell, Curtis, Qu, Yi, Kim, Kyunga, Fabian, Lacramioara, Mohammad, Ariz, Wang, Xian, Robson, Michael I., Krchma, Karen, Wu, Jun, Gonçalves, João, Hodzic, Didier, Wu, Shu, Potter, Daniel, Pelletier, Laurence, Dunham, Wade H., Gingras, Anne-Claude, Sun, Yu, Meng, Jin, Godt, Dorothea, Schedl, Tim, Ciruna, Brian, Choi, Kyunghee, Perry, John R. B., Bremner, Rod, Schirmer, Eric C., Brill, Julie A., Jurisicova, Andrea, McNeill, Helen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Association for the Advancement of Science 2020
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455189/
https://ncbi.nlm.nih.gov/pubmed/32923640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb4591
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