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Accumulation of collagen molecular unfolding is the mechanism of cyclic fatigue damage and failure in collagenous tissues

Overuse injuries to dense collagenous tissues are common, but their etiology is poorly understood. The predominant hypothesis that micro-damage accumulation exceeds the rate of biological repair is missing a mechanistic explanation. Here, we used collagen hybridizing peptides to measure collagen mol...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Sci Adv
Päätekijät: Zitnay, Jared L., Jung, Gang Seob, Lin, Allen H., Qin, Zhao, Li, Yang, Yu, S. Michael, Buehler, Markus J., Weiss, Jeffrey A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Association for the Advancement of Science 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455178/
https://ncbi.nlm.nih.gov/pubmed/32923623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba2795
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