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Accumulation of collagen molecular unfolding is the mechanism of cyclic fatigue damage and failure in collagenous tissues

Overuse injuries to dense collagenous tissues are common, but their etiology is poorly understood. The predominant hypothesis that micro-damage accumulation exceeds the rate of biological repair is missing a mechanistic explanation. Here, we used collagen hybridizing peptides to measure collagen mol...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Zitnay, Jared L., Jung, Gang Seob, Lin, Allen H., Qin, Zhao, Li, Yang, Yu, S. Michael, Buehler, Markus J., Weiss, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455178/
https://ncbi.nlm.nih.gov/pubmed/32923623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba2795
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