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Kynurenines link chronic inflammation to functional decline and physical frailty
Chronic inflammation is associated with physical frailty and functional decline in older adults; however, the molecular mechanisms of this linkage are not understood. A mouse model of chronic inflammation showed reduced motor function and partial denervation at the neuromuscular junction. Metabolomi...
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| Publicat a: | JCI Insight |
|---|---|
| Autors principals: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7455140/ https://ncbi.nlm.nih.gov/pubmed/32814718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.136091 |
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