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ALTERED TRYPTOPHAN DEGRADATION LINKS CHRONIC INFLAMMATION TO FUNCTIONAL DECLINE & FRAILTY IN MICE AND HUMANS

Chronic inflammation is associated with frailty and functional decline in older adults but the molecular mechanisms of this linkage are not well understood. We sought to examine metabolic and physiologic states associated with aging and frailty by analyzing the composition of metabolites in the bloo...

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Bibliografiska uppgifter
I publikationen:Innov Aging
Huvudupphovsmän: Westbrook, Reyhan, Chung, Tae, Lovett, Jacqueline, Ward, Chris, Khadeer, Mohammed, Moaddel, Ruin, Walston, Jeremy, Abadir, Peter
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2019
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6845122/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igz038.3473
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