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Risk-associated alterations in marrow T cells in pediatric leukemia

Current management of childhood leukemia is tailored based on disease risk determined by clinical features at presentation. Whether properties of the host immune response impact disease risk and outcome is not known. Here, we combine mass cytometry, single cell genomics, and functional studies to ch...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Bailur, Jithendra Kini, McCachren, Samuel S., Pendleton, Katherine, Vasquez, Juan C., Lim, Hong Seo, Duffy, Alyssa, Doxie, Deon B., Kaushal, Akhilesh, Foster, Connor, DeRyckere, Deborah, Castellino, Sharon, Kemp, Melissa L., Qiu, Peng, Dhodapkar, Madhav V., Dhodapkar, Kavita M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455136/
https://ncbi.nlm.nih.gov/pubmed/32692727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140179
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