Risk-associated alterations in marrow T cells in pediatric leukemia

Current management of childhood leukemia is tailored based on disease risk determined by clinical features at presentation. Whether properties of the host immune response impact disease risk and outcome is not known. Here, we combine mass cytometry, single cell genomics, and functional studies to ch...

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Publicado en:JCI Insight
Autores principales: Bailur, Jithendra Kini, McCachren, Samuel S., Pendleton, Katherine, Vasquez, Juan C., Lim, Hong Seo, Duffy, Alyssa, Doxie, Deon B., Kaushal, Akhilesh, Foster, Connor, DeRyckere, Deborah, Castellino, Sharon, Kemp, Melissa L., Qiu, Peng, Dhodapkar, Madhav V., Dhodapkar, Kavita M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455136/
https://ncbi.nlm.nih.gov/pubmed/32692727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140179
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