Risk-associated alterations in marrow T cells in pediatric leukemia

Current management of childhood leukemia is tailored based on disease risk determined by clinical features at presentation. Whether properties of the host immune response impact disease risk and outcome is not known. Here, we combine mass cytometry, single cell genomics, and functional studies to ch...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Bailur, Jithendra Kini, McCachren, Samuel S., Pendleton, Katherine, Vasquez, Juan C., Lim, Hong Seo, Duffy, Alyssa, Doxie, Deon B., Kaushal, Akhilesh, Foster, Connor, DeRyckere, Deborah, Castellino, Sharon, Kemp, Melissa L., Qiu, Peng, Dhodapkar, Madhav V., Dhodapkar, Kavita M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455136/
https://ncbi.nlm.nih.gov/pubmed/32692727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140179
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