BET bromodomain proteins regulate transcriptional reprogramming in genetic dilated cardiomyopathy

The bromodomain and extraterminal (BET) family comprises epigenetic reader proteins that are important regulators of inflammatory and hypertrophic gene expression in the heart. We previously identified the activation of proinflammatory gene networks as a key early driver of dilated cardiomyopathy (D...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Antolic, Andrew, Wakimoto, Hiroko, Jiao, Zhe, Gorham, Joshua M., DePalma, Steven R., Lemieux, Madeleine E., Conner, David A., Lee, Da Young, Qi, Jun, Seidman, Jonathan G., Bradner, James E., Brown, Jonathan D., Haldar, Saptarsi M., Seidman, Christine E., Burke, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455078/
https://ncbi.nlm.nih.gov/pubmed/32603312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.138687
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