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Deletion of Mediator 1 suppresses TGFβ signaling leading to changes in epidermal lineages and regeneration

Epidermal lineages and injury induced regeneration are controlled by transcriptional programs coordinating cellular signaling and epigenetic regulators, but the mechanism remains unclear. Previous studies showed that conditional deletion of the transcriptional coactivator Mediator 1 (Med1) changes e...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Oda, Yuko, Nguyen, Thai, Hata, Akiko, Meyer, Mark B., Pike, J. Wesley, Bikle, Daniel D.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455038/
https://ncbi.nlm.nih.gov/pubmed/32857768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0238076
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