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Polo kinase recruitment via the constitutive centromere-associated network at the kinetochore elevates centromeric RNA
The kinetochore, a multi-protein complex assembled on centromeres, is essential to segregate chromosomes during cell division. Deficiencies in kinetochore function can lead to chromosomal instability and aneuploidy—a hallmark of cancer cells. Kinetochore function is controlled by recruitment of regu...
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| Yayımlandı: | PLoS Genet |
|---|---|
| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7455000/ https://ncbi.nlm.nih.gov/pubmed/32810142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008990 |
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