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Synthetic Physical Interactions Map Kinetochore-Checkpoint Activation Regions

The spindle assembly checkpoint (SAC) is a key mechanism to regulate the timing of mitosis and ensure that chromosomes are correctly segregated to daughter cells. The recruitment of the Mad1 and Mad2 proteins to the kinetochore is normally necessary for SAC activation. This recruitment is coordinate...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Ólafsson, Guðjón, Thorpe, Peter H.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978906/
https://ncbi.nlm.nih.gov/pubmed/27280788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.031930
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