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TLR7 in B cells promotes renal inflammation and Gd-IgA1 synthesis in IgA nephropathy
TLR7 has been linked to the pathogenesis of glomerulonephritis, but its precise roles are not clear. In this study, we evaluated the roles of TLR7 in IgA nephropathy (IgAN). TLR7 proteins were abundant in CD19(+) B cells infiltrated in the kidneys of patients with IgAN. The intensities of both intra...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7453916/ https://ncbi.nlm.nih.gov/pubmed/32699192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.136965 |
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