microRNA-630 Regulates Underglycosylated IgA1 Production in the Tonsils by Targeting TLR4 in IgA Nephropathy

IgA nephropathy (IgAN) is the most common primary glomerular disease. The characteristic pathology involves immune complexes formed by the deposition of IgA1 and underglycosylated IgA1 aggregates in the mesangial area, which may be accompanied by the deposition of IgG and/or IgM and complement compo...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Liu, Chan, Ye, Mu-Yao, Yan, Wen-Zhe, Peng, Xiao-Fei, He, Li-Yu, Peng, You-Ming
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725902/
https://ncbi.nlm.nih.gov/pubmed/33324395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.563699
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