Combination of PD-L1 and PVR determines sensitivity to PD-1 blockade

Expression of immune checkpoint ligands (ICLs) is necessary to trigger the inhibitory signal via immune checkpoint receptors (ICRs) in exhausted T cells under tumor immune microenvironment. Nevertheless,to our knowledge, ICL expression profile in cancer patients has not been investigated. Using prev...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Lee, Bo Ryeong, Chae, Sehyun, Moon, Jihyun, Kim, Myeong Joon, Lee, Hankyu, Ko, Hyuk Wan, Cho, Byoung Chul, Shim, Hyo Sup, Hwang, Daehee, Kim, Hye Ryun, Ha, Sang-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7453903/
https://ncbi.nlm.nih.gov/pubmed/32554931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.128633
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