Pulmonary Mycobacterium tuberculosis control associates with CXCR3- and CCR6-expressing antigen-specific Th1 and Th17 cell recruitment

Mycobacterium tuberculosis–specific (M. tuberculosis–specific) T cell responses associated with immune control during asymptomatic latent tuberculosis infection (LTBI) remain poorly understood. Using a nonhuman primate aerosol model, we studied the kinetics, phenotypes, and functions of M. tuberculo...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Shanmugasundaram, Uma, Bucsan, Allison N., Ganatra, Shashank R., Ibegbu, Chris, Quezada, Melanie, Blair, Robert V., Alvarez, Xavier, Velu, Vijayakumar, Kaushal, Deepak, Rengarajan, Jyothi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7453885/
https://ncbi.nlm.nih.gov/pubmed/32554933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.137858
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