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Effects of simvastatin on iNOS and caspase-3 levels and oxidative stress following smoke inhalation injury
The overexpression of inducible nitric oxide synthase (iNOS) induces cell apoptosis through various signal transduction pathways and aggravates lung injury. Caspase-3 is an important protein in the apoptotic pathway and its activation can exacerbate apoptosis. Simvastatin, a hydroxymethyl glutaryl-A...
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| 出版年: | Mol Med Rep |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
D.A. Spandidos
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7453554/ https://ncbi.nlm.nih.gov/pubmed/32945441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2020.11413 |
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