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SIRT1 Mediates Neuropathic Pain Induced by Sciatic Nerve Chronic Constrictive Injury in the VTA-NAc Pathway

BACKGROUND: Mounting evidence has shown that sirtuin 1 (SIRT1), a class III histone deacetylase, alleviated several types of neuropathic pain in the spinal cord and dorsal root ganglion and regulated some aberrant behaviors in the ventral tegmental area (VTA) and the nucleus accumbens (NAc). METHODS...

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Detalhes bibliográficos
Publicado no:Pain Res Manag
Main Authors: Li, Yangyang, Wang, Lei, Zhang, Guotao, Qiao, Xueli, Zhang, Mingxing
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7453274/
https://ncbi.nlm.nih.gov/pubmed/32922581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4245968
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