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Discovery of human coronaviruses pan-papain-like protease inhibitors using computational approaches
The papain-like protease (PL(pro)) is vital for the replication of coronaviruses (CoVs), as well as for escaping innate-immune responses of the host. Hence, it has emerged as an attractive antiviral drug-target. In this study, computational approaches were employed, mainly the structure-based virtua...
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| 發表在: | J Pharm Anal |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Xi'an Jiaotong University
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7453225/ https://ncbi.nlm.nih.gov/pubmed/32874702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2020.08.012 |
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