Live cell imaging and proteomic profiling of endogenous NEAT1 lncRNA by CRISPR/Cas9-mediated knock-in

In mammalian cells, long noncoding RNAs (lncRNAs) form complexes with proteins to execute various biological functions such as gene transcription, RNA processing and other signaling activities. However, methods to track endogenous lncRNA dynamics in live cells and screen for lncRNA interacting prote...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Protein Cell
Main Authors: Chen, Bohong, Deng, Shengcheng, Ge, Tianyu, Ye, Miaoman, Yu, Jianping, Lin, Song, Ma, Wenbin, Songyang, Zhou
Format: Artigo
Jezik:Inglês
Izdano: Higher Education Press 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7452982/
https://ncbi.nlm.nih.gov/pubmed/32458346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-020-00706-w
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