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Mitomycin C enhanced the efficacy of PD-L1 blockade in non-small cell lung cancer

Programmed death ligand 1 (PD-L1) immune checkpoint inhibitors are promising therapeutic agents for treating cancers but the response rate is <20%. Some chemotherapeutic drugs could also activate an anticancer immune response to kill cancer cells, apart from their direct cytotoxicity. Our study i...

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Dettagli Bibliografici
Pubblicato in:Signal Transduct Target Ther
Autori principali: Luo, Min, Wang, Fang, Zhang, Hong, To, Kenneth K. W., Wu, Shaocong, Chen, Zhen, Liang, Shaobo, Fu, Liwu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7452895/
https://ncbi.nlm.nih.gov/pubmed/32855386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-020-0200-4
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