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Tyrosine kinase inhibitors enhanced the efficacy of conventional chemotherapeutic agent in multidrug resistant cancer cells

Multidrug resistance (MDR) triggered by ATP binding cassette (ABC) transporter such as ABCB1, ABCC1, ABCG2 limited successful cancer chemotherapy. Unfortunately, no commercial available MDR modulator approved by FDA was used in clinic. Tyrosine kinase inhibitors (TKIs) have been administrated to fig...

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Bibliografiska uppgifter
I publikationen:Mol Cancer
Huvudupphovsmän: Wu, Shaocong, Fu, Liwu
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817862/
https://ncbi.nlm.nih.gov/pubmed/29455646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0775-3
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