The neuropeptide calcitonin gene-related peptide alpha is essential for bone healing

BACKGROUND: Impaired fracture healing represents an ongoing clinical challenge, as treatment options remain limited. Calcitonin gene-related peptide (CGRP), a neuropeptide targeted by emerging anti-migraine drugs, is also expressed in sensory nerve fibres innervating bone tissue. METHOD: Bone healin...

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Publicat a:EBioMedicine
Autors principals: Appelt, Jessika, Baranowsky, Anke, Jahn, Denise, Yorgan, Timur, Köhli, Paul, Otto, Ellen, Farahani, Saeed Khomeijani, Graef, Frank, Fuchs, Melanie, Herrera, Aarón, Amling, Michael, Schinke, Thorsten, Frosch, Karl-Heinz, Duda, Georg N., Tsitsilonis, Serafeim, Keller, Johannes
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Research paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7452713/
https://ncbi.nlm.nih.gov/pubmed/32853990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102970
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