Leptin Mediated Pathways Stabilize Posttraumatic Insulin and Osteocalcin Patterns after Long Bone Fracture and Concomitant Traumatic Brain Injury and Thus Influence Fracture Healing in a Combined Murine Trauma Model

Recent studies on insulin, leptin, osteocalcin (OCN), and bone remodeling have evoked interest in the interdependence of bone formation and energy household. Accordingly, this study attempts to investigate trauma specific hormone changes in a murine trauma model and its influence on fracture healing...

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Pubblicato in:Int J Mol Sci
Autori principali: Garbe, Anja, Graef, Frank, Appelt, Jessika, Schmidt-Bleek, Katharina, Jahn, Denise, Lünnemann, Tim, Tsitsilonis, Serafeim, Seemann, Ricarda
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7729898/
https://ncbi.nlm.nih.gov/pubmed/33266324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239144
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