Autoinhibition of TRPV6 Channel and Regulation by PIP2

Transient receptor potential vanilloid 6 (TRPV6), a calcium-selective channel possessing six transmembrane domains (S1-S6) and intracellular N and C termini, plays crucial roles in calcium absorption in epithelia and bone and is involved in human diseases including vitamin-D deficiency, osteoporosis...

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Udgivet i:iScience
Main Authors: Cai, Ruiqi, Liu, Xiong, Zhang, Rui, Hofmann, Laura, Zheng, Wang, Amin, Md Ruhul, Wang, Lingyun, Hu, Qiaolin, Peng, Ji-Bin, Michalak, Marek, Flockerzi, Veit, Ali, Declan W., Chen, Xing-Zhen, Tang, Jingfeng
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7452202/
https://ncbi.nlm.nih.gov/pubmed/32829285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101444
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