Adenosine-to-Inosine Editing of Vasoactive MicroRNAs Alters Their Targetome and Function in Ischemia

Adenosine-to-inosine (A-to-I) editing in the seed sequence of microRNAs can shift the microRNAs’ targetomes and thus their function. Using public RNA-sequencing data, we identified 35 vasoactive microRNAs that are A-to-I edited. We quantified A-to-I editing of the primary (pri-)microRNAs in vascular...

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書誌詳細
出版年:Mol Ther Nucleic Acids
主要な著者: van der Kwast, Reginald V.C.T., Parma, Laura, van der Bent, M. Leontien, van Ingen, Eva, Baganha, Fabiana, Peters, Hendrika A.B., Goossens, Eveline A.C., Simons, Karin H., Palmen, Meindert, de Vries, Margreet R., Quax, Paul H.A., Nossent, A. Yaël
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Gene & Cell Therapy 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7452086/
https://ncbi.nlm.nih.gov/pubmed/32814251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.07.020
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