Immunohistochemical scoring of CD38 in the tumor microenvironment predicts responsiveness to anti-PD-1/PD-L1 immunotherapy in hepatocellular carcinoma

INTRODUCTION: Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-associated mortality globally. Immune-checkpoint blockade (ICB) is one of the systemic therapy options for HCC. However, response rates remain low, necessitating robust predictive biomarkers. In the present study, we...

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書誌詳細
出版年:J Immunother Cancer
主要な著者: Ng, Harry Ho Man, Lee, Ren Yuan, Goh, Siting, Tay, Isabel Shu Ying, Lim, Xinru, Lee, Bernett, Chew, Valerie, Li, Huihua, Tan, Benedict, Lim, Sherlly, Lim, Jeffrey Chun Tatt, Au, Bijin, Loh, Josh Jie Hua, Saraf, Sahil, Connolly, John Edward, Loh, Tracy, Leow, Wei Qiang, Lee, Joycelyn Jie Xin, Toh, Han Chong, Malavasi, Fabio, Lee, Ser Yee, Chow, Pierce, Newell, Evan W, Choo, Su Pin, Tai, David, Yeong, Joe, Lim, Tony Kiat Hon
フォーマット: Artigo
言語:Inglês
出版事項: BMJ Publishing Group 2020
主題:
Basic Tumor Immunology
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7451957/
https://ncbi.nlm.nih.gov/pubmed/32847986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000987
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