Cryo-EM and Molecular Docking Shows Myosin Loop 4 Contacts Actin and Tropomyosin on Thin Filaments

The motor protein myosin drives muscle and nonmuscle motility by binding to and moving along actin of thin filaments. Myosin binding to actin also modulates interactions of the regulatory protein, tropomyosin, on thin filaments, and conversely tropomyosin affects myosin binding to actin. Insight int...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Doran, Matthew H., Pavadai, Elumalai, Rynkiewicz, Michael J., Walklate, Jonathan, Bullitt, Esther, Moore, Jeffrey R., Regnier, Michael, Geeves, Michael A., Lehman, William
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7451941/
https://ncbi.nlm.nih.gov/pubmed/32730789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.07.006
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