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C-terminal troponin-I residues trap tropomyosin in the muscle thin filament blocked-state

Tropomyosin and troponin regulate muscle contraction by participating in a macromolecular scale steric-mechanism to control myosin-crossbridge – actin interactions and consequently contraction. At low-Ca(2+), the C-terminal 30% of troponin subunit-I (TnI) is proposed to trap tropomyosin in a positio...

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Bibliografiske detaljer
Udgivet i:Biochem Biophys Res Commun
Main Authors: Lehman, William, Pavadai, Elumalai, Rynkiewicz, Michael J.
Format: Artigo
Sprog:Inglês
Udgivet: 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026701/
https://ncbi.nlm.nih.gov/pubmed/33714756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2021.03.010
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