טוען...
Phase Separation of Toxic Dipeptide Repeat Proteins Related to C9orf72 ALS/FTD
The expansion mutation in the C9orf72 gene is the most common known genetic cause for amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). This mutation can produce five dipeptide repeat proteins (DPRs), of which three are known to be toxic: poly-PR, poly-GR, and poly-GA. The toxic...
שמור ב:
| הוצא לאור ב: | Biophys J |
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| Main Authors: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
The Biophysical Society
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7451925/ https://ncbi.nlm.nih.gov/pubmed/32730793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.07.005 |
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