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Statistical considerations on implementing the MCP-Mod method for binary endpoints in clinical trials
The Multiple Comparison Procedure – Modelling (MCP-Mod) method was qaulified by regulatory agencies (e.g., EMA in 2014 and FDA in 2016) as an efficient statistical method for Phase 2 dose-finding studies when there is uncertainty about dose-response relationship. As this is a relatively new approach...
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| Publicado no: | Contemp Clin Trials Commun |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7451792/ https://ncbi.nlm.nih.gov/pubmed/32875139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2020.100641 |
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