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Pharmacodynamic and Clinical Endpoints for Functional Colonic Disorders: Statistical Considerations

BACKGROUND: Intra- and inter-subject coefficients of variation (COV) of scintigraphic colonic transit (SCT) are well characterized. SCT response to therapy predicts clinical efficacy of experimental medications in lower functional gastrointestinal disorders (FGID). AIM: To compare COVs for bowel fun...

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Detalhes bibliográficos
Main Authors: Zinsmeister, Alan R., Burton, Duane, Camilleri, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529760/
https://ncbi.nlm.nih.gov/pubmed/22918691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-012-2369-z
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