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High affinity rigidified AT(2) receptor ligands with indane scaffolds
Rigidification of the isobutyl side chain of drug-like AT(2) receptor agonists and antagonists that are structurally related to the first reported selective AT(2) receptor agonist 1 (C21) delivered bioactive indane derivatives. Four enantiomer pairs were synthesized and the enantiomers were isolated...
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| Publicado no: | Medchemcomm |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7451071/ https://ncbi.nlm.nih.gov/pubmed/32904210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00402e |
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