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Introducing nitrogen atoms to amidoalkylindoles: potent and selective cannabinoid type 2 receptor agonists with improved aqueous solubility
Previously we identified a series of amidoalkylindoles as potent and selective CB(2) partial agonists. In the present study, we report our continuous effort to improve the aqueous solubility by introducing N atoms to the amidoalkylindole framework. Synthesis, characterization, and pharmacology evalu...
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| Izdano u: | Medchemcomm |
|---|---|
| Glavni autori: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Royal Society of Chemistry
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7451064/ https://ncbi.nlm.nih.gov/pubmed/32904145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00411d |
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