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Silver catalyzed proto- and sila-Nakamura-type α-vinylation of silyl enol ethers with dichloroacetylene. Divergent formation of stereochemically pure tri- and tetrasubstituted olefins.

The silver-catalyzed reaction of silyl enol ethers with dichloroacetylene (DCA) is described. When DCA was used as a solution in diethyl ether, we found that the silyl group was transferred to the vinyl group, resulting in stereochemically pure tetrasubstituted olefins. However, when DCA was used as...

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Vydáno v:Tetrahedron Lett
Hlavní autoři: Li, Lun, Wasik, Kimberly A., Frost, Brian J., Geary, Laina M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7450970/
https://ncbi.nlm.nih.gov/pubmed/32863449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2019.151370
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