Asymmetric Hydrogenation of Unfunctionalized Tetrasubstituted Acyclic Olefins

Asymmetric hydrogenation has evolved as one of the most powerful tools to construct stereocenters. However, the asymmetric hydrogenation of unfunctionalized tetrasubstituted acyclic olefins remains the pinnacle of asymmetric synthesis and an unsolved challenge. We report herein the discovery of an i...

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Foilsithe in:Angew Chem Int Ed Engl
Main Authors: Bigler, Raphael, Mack, Kyle A., Shen, Jeff, Tosatti, Paolo, Han, Chong, Bachmann, Stephan, Zhang, Haiming, Scalone, Michelangelo, Pfaltz, Andreas, Denmark, Scott E., Hildbrand, Stefan, Gosselin, Francis
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141762/
https://ncbi.nlm.nih.gov/pubmed/31794118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201912640
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