Asymmetric Hydrogenation of Unfunctionalized Tetrasubstituted Acyclic Olefins

Asymmetric hydrogenation has evolved as one of the most powerful tools to construct stereocenters. However, the asymmetric hydrogenation of unfunctionalized tetrasubstituted acyclic olefins remains the pinnacle of asymmetric synthesis and an unsolved challenge. We report herein the discovery of an i...

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Vydáno v:Angew Chem Int Ed Engl
Hlavní autoři: Bigler, Raphael, Mack, Kyle A., Shen, Jeff, Tosatti, Paolo, Han, Chong, Bachmann, Stephan, Zhang, Haiming, Scalone, Michelangelo, Pfaltz, Andreas, Denmark, Scott E., Hildbrand, Stefan, Gosselin, Francis
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7141762/
https://ncbi.nlm.nih.gov/pubmed/31794118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201912640
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