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DLBCL with amplification of JAK2/PD-L2 exhibits PMBCL-like CNA pattern and worse clinical outcome resembling those with MYD88 L265P mutation

BACKGROUND: Recently, copy number alteration (CNA) of 9p24.1 were demonstrated in 10% of diffuse large b-cell lymphoma (DLBCL), with gene expression and mutation profiles that were similar to those of primary mediastinal large B-cell lymphoma (PMBCL). However, their CNA-based profile and clinical im...

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Bibliografske podrobnosti
izdano v:BMC Cancer
Main Authors: Xue, Xuemin, Huang, Wenting, Qiu, Tian, Guo, Lei, Ying, Jianming, Lv, Ning
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7450805/
https://ncbi.nlm.nih.gov/pubmed/32854650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07293-3
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