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Enhancing immunotoxin cell-killing activity via combination therapy with ABT-737

Immunotoxins are antibody–toxin fusion proteins directed to kill cancer cells displaying specific target antigens on their surface. Remarkably, immunotoxins directed to CD22 on hairy cell leukemia have produced complete remissions in approximately 60% of patients enrolled in phase I/II trials. For r...

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Bibliografiska uppgifter
I publikationen:Leuk Lymphoma
Huvudupphovsmän: FITZGERALD, DAVID J., MOSKATEL, ELIZABETH, BEN-JOSEF, GAL, TRAINI, ROBERTA, TENDLER, TARA, SHARMA, ASHIMA, ANTIGNANI, ANTONELLA, MUSSAI, FRANCIS, WAYNE, ALAN, KREITMAN, ROBERT J., PASTAN, IRA
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7450489/
https://ncbi.nlm.nih.gov/pubmed/21599608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2011.569961
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