Resolvin E1 Reduces Leukotriene B4–Induced Intracellular Calcium Increase and Mucin Secretion in Rat Conjunctival Goblet Cells

Leukotriene B4 (LTB4) is a major proinflammatory mediator important in host defense, whereas resolvins (Rvs) are produced during the resolution phase of inflammation. The authors determined the actions of both RvE1 and RvD1 on LTB4–induced responses of goblet cells cultured from rat conjunctiva. The...

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Bibliographic Details
Published in:Am J Pathol
Main Authors: Yang, Menglu, Bair, Jeffrey A., Hodges, Robin R., Serhan, Charles N., Dartt, Darlene A.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7450248/
https://ncbi.nlm.nih.gov/pubmed/32561135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2020.06.001
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