Resolvin D2 elevates cAMP to increase intracellular [Ca(2+)] and stimulate secretion from conjunctival goblet cells

Under physiologic conditions, conjunctival goblet cells (CGCs) secrete mucins into the tear film to preserve ocular surface homeostasis. Specialized proresolving mediators (SPMs), like resolvins (Rvs), regulate secretion from CGCs and actively terminate inflammation. The purpose of this study was to...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:FASEB J
Egile Nagusiak: Botten, Nora, Hodges, Robin R., Li, Dayu, Bair, Jeffrey A., Shatos, Marie A., Utheim, Tor P., Serhan, Charles N., Dartt, Darlene A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Federation of American Societies for Experimental Biology 2019
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593886/
https://ncbi.nlm.nih.gov/pubmed/31013438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802467R
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